Xinhua Daily Telegraph reporter Leon, Liu Yide and He Shuchen.

　　The maximum precipitation exceeds 100 mm, the deepest snow on the road reaches 2 meters, the road traffic is almost paralyzed, a large number of sheds collapse, and the direct economic loss of the initial nuclear power exceeds 660 million yuan … … Recently, the strongest snowstorm weather in 70 years hit Tongliao City, Inner Mongolia Autonomous Region.

　　In the face of record-breaking disastrous weather, local cadres in party member rushed to the front line to face the snowstorm for the first time, putting the safety and warmth of the affected people in the first place, uniting and leading the masses to gather endless concentric forces to fight the snowstorm, quickly gathering into a new force to declare war on the snowstorm, and building a disaster-resistant fortress that the wind can’t collapse and the snow can’t collapse.

　　On November 11th, in the south marshalling yard of Tongliao Station of China Railway Shenyang Bureau Group Co., Ltd., officers and men of the armed police were cleaning up the snow. Xinhua News Agency reporter Lian Zhenshe

　　Snow storm, party flag flying.

　　170,000 party member cadres charged in the front line.

　　Take snow as the number and snow as the order. In the process of fighting against the severe snowstorm, 170,000 party member cadres in Tongliao City charged in the front line. The cold can’t stop their enthusiasm for serving the people, and the wind and snow can’t blow away their enthusiasm for the masses. Communist party member has become the strongest force in disaster relief.

　　The disaster is on the front line, and the disaster is at the grassroots level. After the arrival of the strong snowstorm, the majority of cadres in party member did their duty and did not shrink back, and quickly went deep into the places where the snow and ice were the most serious, the snow removal was the most difficult and the people needed it most.

　　"Lao zhang, the stove burns well? Is there enough firewood? " "Enough firewood, don’t worry about me." In Qingjia, an old military family in Zhang Ke, He Changhui did not even take a sip of hot water and went to the next one; "He Zhishu, there are no other difficulties in my family, that is, my legs and feet are not neat, and the snow in the yard can be adjusted?" "Don’t worry about this, I will organize party member and village cadres to help you." At Bao Gang’s home for the disabled, He Changhui said that he was calling to organize manpower.

　　On November 8-9, the scene of a man riding a chestnut horse and stepping into the house through the snow was impressive. The rider is He Changhui, the branch secretary of Dihe Village, Changsheng Town, Horqin Left Wing Houqi.

　　On November 11th, at the south marshalling yard of Tongliao Station of China Railway Shenyang Bureau Group Co., Ltd., officers and men of the armed police prepared to clear the snow. Xinhua News Agency reporter Lian Zhenshe

　　In the days when the snow was heaviest, the whole village was covered with snow. He Changhui was worried that the villagers, especially the low-income households and elderly people living alone, would be affected, but he was afraid of being trapped when driving, so he chose a horse with high strength at home. "It’s still our place in the snow ‘ Bmw ’ So good! "

　　"This is the time when the masses need us most. party member cadres have to rush to the front line and solve practical difficulties for the people. This is the true nature of Communist party member." He Changhui said firmly.

　　There are also many cadres in party member who show their talents in times of crisis and protect people’s lives and property with actions. Some fire-fighting and rescue officers and soldiers risked the snow to crush the rescue passage at any time to rescue the trapped people; Some police officers trudged for hours in the snowstorm without breakfast in order to find the lost cattle for the masses, and finally completed the task … …

　　On November 11th, in the south marshalling yard of Tongliao Station of China Railway Shenyang Bureau Group Co., Ltd., officers and men of armed police cleared the snow (photo of drone). Xinhua News Agency reporter Lian Zhenshe

　　In the severe snowstorm weather, it is the grassroots party organizations that give full play to the role of "fighting bastion" and turn "waiting for the masses to find services" into "taking the initiative to deliver services", so that the masses can eat "reassurance" for the first time in rare disastrous weather.

　　There are more than 1,600 bungalows in the Oriental Pearl Community in Horqin District, Tongliao City. Because it is located in the nest wind zone, the snow is as deep as one meter 78, and many residents once did not see the sun. The Party Working Committee of Dongjie Street, which belongs to the community, immediately organized party member and volunteers to form a 200-person "commando".

　　Faced with a huge workload, the "commando team" began to walk into the house on November 8, shoveling and shouldering, and finally eased the snow problem. "Seeing so many young men helping to clean up the snow in the yard and hutong, my heart that has been hanging has also landed, otherwise I really don’t know how to go out." Bao Siqin, a 75-year-old man who lives alone in the bungalow area, said.

　　On November 11, in the suburbs of Tongliao, working vehicles cleared the snow. Xinhua News Agency reporter Lian Zhenshe

　　In the western and northern pastoral areas of Tongliao City, many herders live in scattered areas, far away from the township. There are more than 300 scattered herders in Yihe Tara Town, Kailu County. After the snowstorm, local party member cadres and volunteers acted immediately to send materials to herders who were trapped by heavy snow and were inconvenient to travel.

　　Affected by the heavy snow, several straw bales of Sumu in the south of Zhalute Banner were buried in the grassland by heavy snow, and some herders were short of forage. "The snow hasn’t stopped yet, and Sumu and Gacha cadres went to the door to understand the situation." Su He, a herder, said that at that time, they registered the shortage of forage and the damage of sheds. "Now the road is basically open, and the forage that Gacha helped to contact will be delivered soon." Su He said with a smile that when party member cadres came, everyone had a bottom in their hearts. "The party and the government are the strong backing of everyone."

　　Rare disastrous weather also brings great challenges to urban infrastructure. In order to ensure people’s stable life at home, teams of "party member Commando" and "party member Service Team" charged at the front line of protecting people’s livelihood in the snowstorm.

　　On November 11th, in Tongliao city, residents spontaneously cleared the snow. Xinhua News Agency reporter Lian Zhenshe

　　In the dark snowy night, the beams of several strong flashlights shine into the night sky from time to time; Under the irradiation of the light beam, the flying snowflakes are dazzling; Several figures trudged through the snow with one foot deep and one foot shallow. Occasionally, one person fell into chest-high snow, and everyone hurried over to pull it out … …

　　This is the scene where the members of the emergency rescue team of the Fifth Water Plant of Tongliao Water Supply Co., Ltd. checked the faulty line at 4 am on the 7th. The Fifth Waterworks undertakes the drinking water demand of more than 200,000 people in the main city, but there is something wrong with the power supply line of the waterworks, and the water supply in the urban area is cut off in a large area.

　　After receiving the task at 3: 40 in the morning, the fifth water plant, which has been fully staffed all day, immediately started the emergency mechanism. At about 3: 50am, five party member employees voluntarily signed up to join the "Emergency Commando", and six ordinary employees also responded positively. This 11-member team is led by Sun Tiandong, an experienced 58-year-old party member.

　　"Now there are professional instruments, it is not difficult to find the fault point of the line, but it is really difficult in this weather!" Sun Tiandong said that the car can’t move and can only walk; The poles of the line were all in the farmland, and the ditches were covered with snow. If you were not careful, the whole person sank in.

　　On November 11th, at Tongliao Railway Station, the staff removed snow on the railway line. Xinhua News Agency reporter Liu Lei photo

　　The 11 soldiers split into two roads, and the fault point was locked after 6 o’clock in the snowstorm. After intense maintenance, they have become "snowmen" when the feedback of "the water supply in the city is restored and the water pressure is normal" came from the phone.

　　Blizzard is also a great test for the safety of residents’ electricity consumption. The clothes mixed with sweat and snow water have been frozen stiff, and the legs and feet are numb with cold. This is an unforgettable equipment maintenance for 26-year-old Sun Dehua.

　　Sun Dehua is a party member employee of Tongliao Power Supply Company of State Grid Inner Mongolia East Electric Power Co., Ltd. At noon on the 9th, his "Communist party member Service Team" received an urgent task and immediately set out to repair a box-type substation cabinet.

　　On November 11th, in the south marshalling yard of Tongliao Station of China Railway Shenyang Bureau Group Co., Ltd., officers and men of the armed police and railway staff cleared the snow (photo of drone). Xinhua News Agency reporter Lian Zhenshe

　　At the scene, the half-meter-high base of the substation cabinet has been covered with snow, and there is thick snow above the cabinet. Clear the snow, bend down to find the fault, and prepare to replace the parts … … After more than 4 hours, the faulty parts were replaced and the power supply of more than 180 households and shops returned to normal. "Power equipment maintenance requires both electrician knowledge and good body." Sun Dehua said that almost every time he was repaired, he was sweating all over.

　　There are 151 "Communist party member Service Teams" active in this company. They are on standby all day and patrol around the clock to ensure that people can use electricity stably and safely in snowstorm weather.

　　With a pure heart, you are not afraid of the wind and snow, and faith, like fire, will melt hard ice. In the face of the disaster, more than 170,000 local party member cadres rushed to the front line and fought at the forefront, practicing their initial mission in the front line of snow removal and disaster relief, and letting the bright red party flag fly high.

　　On November 11th, in Tongliao Yunda Green Agricultural and Sideline Products Wholesale Market, the staff were carrying vegetables. Xinhua News Agency reporter Liu Lei photo

　　Fighting in the "snow" and fighting against disasters.

　　Gather Tongliao’s strength to fight the snowstorm.

　　Although the strongest snowstorm in the past 70 years is threatening, with the vanguard and exemplary role of the cadres in party member, Tongliao has a strong disaster-resistant force, which is enough to shelter from the wind and snow.

　　When the wind was the craziest and the snow was the heaviest, party member cadres and the masses joined forces to fight against the wind and snow, trying to minimize the disaster losses.

　　One greenhouse has become a long strip of snow bags; Dozens of people in boots and down jackets are struggling to clean up 20 or 30 centimeters of snow on the shed; The creaking sound of stepping on snow, the puffing sound of falling snow, and everyone’s gasping sound are all one … … This is the snow removal scene of an agricultural facility area in Guangming Village, Daqintala Town, Naiman Banner on the morning of the 9th.

　　On November 11th, in Tongliao Yunda Green Agricultural and Sideline Products Wholesale Market, the staff were sorting potatoes. Xinhua News Agency reporter Lian Zhenshe

　　There are 37 fruit and vegetable greenhouses here. Fortunately, according to the early warning of the meteorological department before the blizzard, the greenhouses were strengthened without collapse, but the snow has seriously affected the photosynthesis of crops. "The village organized self-help. When everyone saw someone planning, they all came out to work with the snow. Many hands make light work. Now the snow in the greenhouse has been cleared!" Wang Guofeng, secretary of the village Party branch, said.

　　In Aolibugao Town, Horqin District, Tongliao City, young and strong villagers actively joined the "Disaster Relief and Self-help Commando" to clean up the snow-buried cowshed in time, retrieve the lost cattle and recover the economic losses of millions of yuan; In Tongliao Economic and Technological Development Zone, more than 20 greenhouses in Wang Yu’s country, a farmer in Sihetun Village, Liaohe Town, were damaged to varying degrees. When the heavy workload of self-rescue and slow progress made him sad, the village cadres who knew the situation came to reinforce with mechanical vehicles and volunteers … …

　　Under the comprehensive mobilization and professional guidance of relevant departments, farmers began to dispose of "food on the ground", and herders carried out disease prevention and transportation of forage. Horqin land was full of scenes of disaster relief and self-help.

　　Tongliao’s corn production accounts for nearly one-third of the whole region, and the grain output has exceeded 10 billion Jin for many years, which is known as the "granary of Inner Mongolia". The snowstorm caused the corn that farmers hung outdoors to be covered with snow. As the temperature rose after the snow, it was easy to cause mildew. To this end, all departments timely issued notices for "laying grain on the ground" after snow, and the vast number of farmers helped each other to carry out the action of clearing snow and protecting grain.

　　On November 10th, cars were covered with snow in Tongliao, Inner Mongolia. Xinhua News Agency reporter Lian Zhenshe

　　The corn in the courtyard is covered with a thick "snow quilt", and five or six boys are using shovels to "save" the grain … … On the morning of the 13th, Sanjiazi Gacha Group in Kulun Town, Kulun Banner, in the home of villager Dahubai Yila, neighbors were gathering at his home to work together. "The snow is more than half a meter, and I can’t make it myself. When I saw the notice issued in the flag on the 11 th, everyone joined forces to clear the snow and dump it. Today it’s my turn!" Dahubai Yila said that his family has hit more than 30,000 kilograms of corn this year, all of which are hanging in the yard. "The temperature and moisture are reminded, and the notice in the flag is quite professional. Everyone can work together and scientifically protect the grain, which will definitely reduce the loss."

　　There are more than 2 million beef cattle in Tongliao City, and the snowstorm has caused a large number of herdsmen’s sheds to be damaged and forage materials to be short-term. The relevant departments timely issued epidemic prevention reminders, and a large number of front-line staff visited herdsmen door to door to contact and dispatch forage and provide epidemic prevention guidance.

　　"This year, I was busy updating the shed. The grass planted on nearly 500 acres of grassland at home was buried in the snow without taking care of it." Bai Yuchun, a 41-year-old herder in Baiyintumen Gacha, Wulijimuren Sumu, Zhalute Banner, told the local cadres at home at noon on the 9th.

　　Bai Yuchun and four herdsmen live not far away, but it is nearly 20 kilometers away from Sumu Town. "We began to clear the snow for the cowshed and yard at 5 am that day." He said that when their families were tired at noon, they drove forklifts to clear the way in the snow to understand the situation. "It was timely to use forklifts to help us clear the snow and bring guidance on animal disease prevention and control!"

　　In the urban area, residents take the initiative to make efforts at home to make the roads smoother.

　　West Gacha of Longwang Temple in Advanced Sumu, Kulun Banner, which was covered with snow on November 13th (photo of drone). Xinhua News Agency reporter Lian Zhenshe

　　"The community is our home, and it is also our responsibility and obligation to clean up our home." On the morning of the 12th, Cao Fengjie, a resident of Diwang Garden Community in Tongliao Economic and Technological Development Zone, and a group of neighbors, wearing cotton caps and masks, were cleaning up the snow on both sides of the road with big shovels. Under the leadership of the community grid staff, some residents shovel snow, some push piles, and some ship … … Everyone is full of energy. Seeing that the road surface is no longer difficult to walk because of snow and ice, the elderly residents passing by have praised it.

　　Due to the thick snow in Jindi Community, some roads have been covered with ice and snow mixture, so it is difficult to clean up. Seeing that the staff were struggling to clean up, a group of enthusiastic residents joined. They have a clear division of labor: the people in the front row use shovels to remove snow and break the accumulated ice, and the people behind them quickly clean it up. After fighting in Qi Xin on the morning of 12th, most of the accumulated snow and ice near the residential area was cleared.

　　"Community party member, grid workers, and people in the property, clearing snow is also for everyone. We can contribute and make a contribution." Zhang Yongzhu, a resident of Lanwan Dongjun Community in Tongliao Economic and Technological Development Zone, said, "It’s very cold outside and it’s very tiring to clear the snow, but everyone is working together in Qi Xin. This spirit and energy are very exciting. I finished the work in one morning!"

　　At present, the snowstorm in Tongliao City has passed, but the struggle against the snowstorm has not stopped. One by one, they never give up, actively save themselves, and the scene of giving charcoal in the snow and helping each other continues.

　　On November 13th, at Hongqi Primary School in Hure Banner, teachers and parents were cleaning up the snow. Xinhua News Agency reporter Lian Zhenshe

　　Scientific response, assistance from all directions

　　Institutional advantage shows the ultimate strength in the snow

　　The rare snowstorm is a disaster, but the continuous improvement of governance capacity in recent years has greatly enhanced the comprehensive strength of urban disaster resistance.

　　Thanks to the increasingly dense and accurate meteorological information collection system, Tongliao Meteorological Bureau issued the first meteorological disaster warning on November 3. According to the experience of dealing with heavy snow in winter last year, Tongliao Municipal Party Committee and Municipal Government immediately responded urgently in advance.

　　In recent years, in the process of successfully establishing "national civilized city" and "national health city", Tongliao City has a smoother urban management system and more refined governance capacity. After the start of the emergency response, emergency vehicle standby, snow removal equipment deployment, front-line personnel organization, people’s livelihood material security, safety and disaster prevention publicity and other work were rapidly promoted in an orderly manner with the close cooperation of various departments.

　　The city’s fire rescue, public security organs, medical institutions, all on-the-job, all-day standby, to ensure that the masses can come when they need it, can fight when they come, and win the battle; Important livelihood units such as water supply, power supply and heating have sufficient basic materials and emergency forces on standby to ensure the basic livelihood of the people; All counties and counties in each banner will allocate a large amount of manpower and machinery in advance, ready to start the snow clearing and traffic protection operation at any time … … On the eve of the snowstorm, all localities and departments in Tongliao City have been "waiting for the pillow", waiting to be tested by the blizzard.

　　Because of this, although this snowstorm is the worst in the local area in 70 years, far exceeding the local immediate emergency response ability, it can still survive the severe snowstorm weather process for more than 110 hours without confusion.

　　In these more than 110 hours, the whole city started to move. No one stays out of the way and warms their hearts one by one, making the city surge with warm current everywhere.

　　This warm-hearted move is a bowl of hot noodles provided free of charge by enthusiastic merchants. After several days of snowfall, many shops in Baoan Town of Naiman Banner were closed, but a pulled noodle restaurant named "Fuxiangju" was particularly busy. "Let everyone eat a hot noodle for free to drive away the cold." Yang Fusheng and his wife said while cooking noodles for snow workers. There is a sudden drop of snow, and many volunteers clean up the snow every day. Seeing this, noodle shop owner Yang Fusheng decided to open the shop, but not to make money, but to provide all volunteers, forklift drivers and patrolmen with hand-pulled noodles for free all day.

　　This warm-hearted move is a life channel that comes out from the shoulders. At 19: 00 on the 8th, Jimou, who was suffering from uremia in Alu West Community of Hure Banner, turned to the town police station for help because he was in urgent need of dialysis. Heavy snow blocked the road. After the police arrived in the snow, they leaned over and picked up Jimou, flew hundreds of meters to the main road, and then were relayed to the hospital by rescue vehicles. Jimou said: "It’s hard to walk on your own in the snowy day. It’s not easy for them to carry me. Without them, my life may be in danger today."

　　The more you face difficulties, the more you can demonstrate the institutional advantages. In the face of disaster, Tongliao has never been a city fighting.

　　On the 10th, news such as "Come on Tongliao, Meng D is coming" and "Support Tongliao, Meng F is coming" screened the circle of friends of local people. On the expressway leading to Tongliao City, the "Meng D" in Chifeng City and the "Meng F" in Xing ‘an League stretch for several miles, respectively, from north to south to "snow". On a dump truck, a banner with the words "mountains and rivers are connected, snow and snow are in the same sky, Chifeng and Tongliao people are holding hands" flutters in the snow.

　　"We have two shifts, day and night, ‘ People don’t rest when they rest ’ , fully clear the snow. " Wu Guomin, captain of the rescue team supporting Tongliao Economic and Technological Development Zone in Chifeng City, said. At 1 am on the 11th, after a 10-hour trek in the snow, the 51-car Chifeng Support Team arrived at the local area and started snow removal overnight.

　　On November 11th, in the south marshalling yard of Tongliao Station of China Railway Shenyang Bureau Group Co., Ltd., officers and men of the armed police were cleaning up the snow. Xinhua News Agency reporter Lian Zhenshe

　　Outside Tongliao City, there are allied cities and fire lines connected by mountains and rivers, and there are counties, districts and cities under the jurisdiction of the city to fight side by side. Holingol City, Zhalute Banner, Kailu County and other places, which are relatively less affected by the snowfall, have dispatched vehicles to rescue the severely affected areas one after another, and Qi Xin has made concerted efforts to remove snow and clear ice.

　　"When we arrived, when we saw the car on the road, we took a tip and it was covered with snow." Shen Ruibin, the driver of the road leveling machine, came from a private enterprise in Huolinguole City. "As soon as we saw the notice, we voluntarily signed up. When we had an epidemic, the surrounding counties helped us. Now they have difficulties and we have to carry them together!" Shen Ruibin said that sometimes at noon, they went to a remote place to shovel snow, and it was too late to have lunch. The local staff drove several kilometers to send them lunch. "When they got it, the box lunch was still hot!"

　　"We cleaned up the streets in the main city before. Due to the lack of mechanical equipment, snow can only be piled on both sides of the road." Zhang Junhua, Party Secretary of the Urban Management Comprehensive Administrative Law Enforcement Bureau in Horqin District, Tongliao City, said, "Brother League City and Qixian County have given us timely help to make up for the shortage of equipment and manpower and shorten our workload for three or four days."

　　As of 14: 00 on the 12th, Tongliao Red Cross Society has received donations of more than 6.9 million yuan from all walks of life. At present, 4 expressways, 15 national and provincial trunk roads, and more than 2,800 county and township roads in Tongliao City have been restored, with sufficient living materials, stable power supply and heating, and post-disaster disposal work is being carried out steadily.

　　After the snowstorm, Tongliao, which shed its heavy "snow coat", was cold, but warm.

　　Ambaviruzumab injection

　　Romisevir monoclonal antibody injection

　　● This is the first approved Covid-19 neutralizing antibody combination therapy drug with independent intellectual property rights in China.

　　● It can reduce the risk of hospitalization and death of COVID-19 patients with high clinical progression by 80%.

　　On July 7th, Tengshengbo Pharmaceutical and its holding company Tengsheng Huachuang announced that the combination therapy of COVID-19 neutralizing antibody Anbavir monoclonal antibody and Romisvir monoclonal antibody was commercialized in China, and the first batch of antibody drugs had been released commercially. This drug is also the first approved domestic COVID-19 neutralizing antibody combination therapy drug.

　　How effective is this COVID-19 specific medicine? Can ordinary families afford the cost of treatment? On July 8th, Luo Yongqing, president and general manager of Tengshengbo Pharmaceutical in Greater China, disclosed the pricing and production capacity of neutralizing antibody drugs in COVID-19.

　　Luo Yongqing said that overseas similar products generally adopt the mode of government procurement, and each person is in the range of 1,500-2,000 US dollars. The combination therapy of Tengsheng Bo Medicine will be priced within 10,000 yuan, which is lower than the global level.

　　It is reported that the first batch of thousands of medicines were sent to Shenzhen Third People’s Hospital. The next step will be to distribute the drugs to the whole country through three distributors: China Resources Medicine, Shanghai Medicine and Sinopharm Holdings.

　　Why are new drugs?

　　Pricing is so expensive?

　　According to reports, at present, the combination therapy of Ambroxobin and Romisvir is listed in China and adopts the independent pricing model. Overseas, the business model of the drug is the government procurement model. For example, if the US government purchases millions of people, the government procurement price for each person is between 1,500 and 2,000 US dollars. The domestic price of this specific drug made in COVID-19 is lower than the purchase price in the United States, basically within 10,000 RMB.

　　Luo Yongqing, President and CEO of Tengshengbo Pharmaceutical, revealed that the company invested more than US$ 200 million before and after the research and development of Anbavir monoclonal antibody and Romisvir monoclonal antibody to ensure the smooth development and commercialization. He said that the price of new drugs should comprehensively consider many factors such as dosage and pharmacoeconomic value. When Tengshengbo first designed the COVID-19 neutralizing antibody, it considered the possible mutation of the virus in the future, so it designed a pair of antibodies instead of one antibody.

　　"Our current dosage is 1000 mg of Ambavirumab plus 1000 mg of Romisvir, a total of 2,000 mg, which is the highest dosage among all approved neutralizing antibodies at home and abroad." Luo Yongqing said.

　　This specific medicine

　　Can I take medical insurance?

　　The price of this COVID-19 specific medicine is close to 10,000 yuan, which is a heavy burden for many low-income families. However, the good news is that patients can take medical insurance to settle accounts.

　　Since March 22 this year, several provincial and municipal medical insurance bureaus have successively included the combination therapy of Ambavirumab and Romisimab into the payment scope of local medical insurance funds. In contrast, another neutralizing antibody that has been approved for marketing in the world — — AstraZeneca Evusheld was also used in the pioneer area of international medical tourism in Boao Lecheng, Hainan this month through relevant policies. The indication is prevention before exposure of COVID-19, and the price of two injections at one time is 13,300 yuan, which cannot be settled by medical insurance.

　　In terms of production capacity, Tengshengbo Pharmaceutical said that it will make production plans according to the needs of domestic and foreign markets, and has reached cooperation with Yaoming Bio, a leading global biopharmaceutical contract development and production (CDMO) enterprise, which can match production capacity according to global and domestic epidemic prevention needs.

　　This new drug has been first used in Shenzhen Third People’s Hospital. At the same time, Tengshengbo Pharmaceuticals has entrusted three major distributors, namely China Resources Medicine, Sinopharm Holdings and Shanghai Pharmaceuticals. "They have the ability to cover any part of the country. Once there is demand, they can deliver it quickly. Coverage is not a problem." Luo Yongqing said.

　　After vaccination

　　Do you need a specific medicine?

　　At present, vaccines, small molecule drugs and neutralizing antibody drugs play different roles in COVID-19 epidemic response.

　　"Neutralizing antibodies can make up for the shortcomings faced by vaccines and small molecular drugs when used in immunocompromised people." Li Yan, chief medical officer of Tengshengbo Medicine, said that some people with weak immunity may not be suitable for COVID-19 vaccine, and even if they are vaccinated, they can’t produce enough antibodies because of their weak immune response, so the vaccine can’t play a preventive role. For this part of the population, injecting neutralizing antibody can produce "immediate" effect.

　　At present, Tengshengbo Pharmaceutical has received demand from more than 20 provinces and cities. However, the future market space of drugs mainly depends on the change of epidemic prevention policy and the influence of future epidemic evolution. "As BA.5 and BA.4 become the dominant Covid-19 (strain) overseas, it may also spread to China. I think this will create an application demand. " Luo Yongqing said.

　　According to national business daily and Beijing Daily client.

　　Special surprise

　　Double antibody+large dose

　　Studies have shown that it is effective for the "worst mutant"

　　On July 6th, WHO Director-General Tan Desai said that Omicron mutant strain BA.5 has been detected in 83 countries and regions, and BA.4 has been detected in 73 countries and regions. At present, BA.5 has replaced BA.2 as the main strain in the world. The latest weekly report on the global COVID-19 epidemic released by WHO shows that the number of COVID-19 cases in the world has increased for the fourth consecutive week, reaching the highest level since March this year.

　　Happily, the first domestic COVID-19 specific drug showed broad spectrum in the face of constantly changing viruses. "The results just obtained on the 7 th show that the combination therapy of Ambavirumab/Romisvir has shown a good virus inhibition effect on Omicron mutants BA.4 and BA.5." Lu Hongzhou, president of the Third People’s Hospital of Shenzhen, said that laboratory pseudovirus research shows that the antibody concentration required for the drug to inhibit 90% of BA.4 or BA.5 virus is very low, which can meet the effective standards set by the US Food and Drug Administration.

　　Zhang Linqi, the head of the R&D team and a professor at Tsinghua University Medical College, told reporters that everyone uses the method of screening "antibody pairs" to avoid virus escape, but they are particular about screening "antibody pairs". The two antibodies must cooperate with each other and be able to play a combination boxing, for example, to identify different positions of the virus. Based on the detailed study of the interaction process between virus and antibody, the team finally screened out the "antibody pair" that can inhibit the virus in time and space from 206 candidate antibodies and found the "best partner".

　　Luo Yongqing said that when the antibody was originally designed, the possible virus mutation in the future was considered, so it was not a single antibody, but a pair of antibodies; At the same time, considering the efficacy of the combination therapy, the dosage of "Anbavir monoclonal antibody (1000 mg)+Romisvir monoclonal antibody (1000 mg)" was finally determined, which is also the highest dose of neutralizing antibodies approved at home and abroad.

　　"Even if there are further virus mutations in the future, we can consider other methods, such as continuing to increase the dose to achieve the antiviral effect." Luo Yongqing said.