Ambaviruzumab injection

　　Romisevir monoclonal antibody injection

　　● This is the first approved Covid-19 neutralizing antibody combination therapy drug with independent intellectual property rights in China.

　　● It can reduce the risk of hospitalization and death of COVID-19 patients with high clinical progression by 80%.

　　On July 7th, Tengshengbo Pharmaceutical and its holding company Tengsheng Huachuang announced that the combination therapy of COVID-19 neutralizing antibody Anbavir monoclonal antibody and Romisvir monoclonal antibody was commercialized in China, and the first batch of antibody drugs had been released commercially. This drug is also the first approved domestic COVID-19 neutralizing antibody combination therapy drug.

　　How effective is this COVID-19 specific medicine? Can ordinary families afford the cost of treatment? On July 8th, Luo Yongqing, president and general manager of Tengshengbo Pharmaceutical in Greater China, disclosed the pricing and production capacity of neutralizing antibody drugs in COVID-19.

　　Luo Yongqing said that overseas similar products generally adopt the mode of government procurement, and each person is in the range of 1,500-2,000 US dollars. The combination therapy of Tengsheng Bo Medicine will be priced within 10,000 yuan, which is lower than the global level.

　　It is reported that the first batch of thousands of medicines were sent to Shenzhen Third People’s Hospital. The next step will be to distribute the drugs to the whole country through three distributors: China Resources Medicine, Shanghai Medicine and Sinopharm Holdings.

　　Why are new drugs?

　　Pricing is so expensive?

　　According to reports, at present, the combination therapy of Ambroxobin and Romisvir is listed in China and adopts the independent pricing model. Overseas, the business model of the drug is the government procurement model. For example, if the US government purchases millions of people, the government procurement price for each person is between 1,500 and 2,000 US dollars. The domestic price of this specific drug made in COVID-19 is lower than the purchase price in the United States, basically within 10,000 RMB.

　　Luo Yongqing, President and CEO of Tengshengbo Pharmaceutical, revealed that the company invested more than US$ 200 million before and after the research and development of Anbavir monoclonal antibody and Romisvir monoclonal antibody to ensure the smooth development and commercialization. He said that the price of new drugs should comprehensively consider many factors such as dosage and pharmacoeconomic value. When Tengshengbo first designed the COVID-19 neutralizing antibody, it considered the possible mutation of the virus in the future, so it designed a pair of antibodies instead of one antibody.

　　"Our current dosage is 1000 mg of Ambavirumab plus 1000 mg of Romisvir, a total of 2,000 mg, which is the highest dosage among all approved neutralizing antibodies at home and abroad." Luo Yongqing said.

　　This specific medicine

　　Can I take medical insurance?

　　The price of this COVID-19 specific medicine is close to 10,000 yuan, which is a heavy burden for many low-income families. However, the good news is that patients can take medical insurance to settle accounts.

　　Since March 22 this year, several provincial and municipal medical insurance bureaus have successively included the combination therapy of Ambavirumab and Romisimab into the payment scope of local medical insurance funds. In contrast, another neutralizing antibody that has been approved for marketing in the world — — AstraZeneca Evusheld was also used in the pioneer area of international medical tourism in Boao Lecheng, Hainan this month through relevant policies. The indication is prevention before exposure of COVID-19, and the price of two injections at one time is 13,300 yuan, which cannot be settled by medical insurance.

　　In terms of production capacity, Tengshengbo Pharmaceutical said that it will make production plans according to the needs of domestic and foreign markets, and has reached cooperation with Yaoming Bio, a leading global biopharmaceutical contract development and production (CDMO) enterprise, which can match production capacity according to global and domestic epidemic prevention needs.

　　This new drug has been first used in Shenzhen Third People’s Hospital. At the same time, Tengshengbo Pharmaceuticals has entrusted three major distributors, namely China Resources Medicine, Sinopharm Holdings and Shanghai Pharmaceuticals. "They have the ability to cover any part of the country. Once there is demand, they can deliver it quickly. Coverage is not a problem." Luo Yongqing said.

　　After vaccination

　　Do you need a specific medicine?

　　At present, vaccines, small molecule drugs and neutralizing antibody drugs play different roles in COVID-19 epidemic response.

　　"Neutralizing antibodies can make up for the shortcomings faced by vaccines and small molecular drugs when used in immunocompromised people." Li Yan, chief medical officer of Tengshengbo Medicine, said that some people with weak immunity may not be suitable for COVID-19 vaccine, and even if they are vaccinated, they can’t produce enough antibodies because of their weak immune response, so the vaccine can’t play a preventive role. For this part of the population, injecting neutralizing antibody can produce "immediate" effect.

　　At present, Tengshengbo Pharmaceutical has received demand from more than 20 provinces and cities. However, the future market space of drugs mainly depends on the change of epidemic prevention policy and the influence of future epidemic evolution. "As BA.5 and BA.4 become the dominant Covid-19 (strain) overseas, it may also spread to China. I think this will create an application demand. " Luo Yongqing said.

　　According to national business daily and Beijing Daily client.

　　Special surprise

　　Double antibody+large dose

　　Studies have shown that it is effective for the "worst mutant"

　　On July 6th, WHO Director-General Tan Desai said that Omicron mutant strain BA.5 has been detected in 83 countries and regions, and BA.4 has been detected in 73 countries and regions. At present, BA.5 has replaced BA.2 as the main strain in the world. The latest weekly report on the global COVID-19 epidemic released by WHO shows that the number of COVID-19 cases in the world has increased for the fourth consecutive week, reaching the highest level since March this year.

　　Happily, the first domestic COVID-19 specific drug showed broad spectrum in the face of constantly changing viruses. "The results just obtained on the 7 th show that the combination therapy of Ambavirumab/Romisvir has shown a good virus inhibition effect on Omicron mutants BA.4 and BA.5." Lu Hongzhou, president of the Third People’s Hospital of Shenzhen, said that laboratory pseudovirus research shows that the antibody concentration required for the drug to inhibit 90% of BA.4 or BA.5 virus is very low, which can meet the effective standards set by the US Food and Drug Administration.

　　Zhang Linqi, the head of the R&D team and a professor at Tsinghua University Medical College, told reporters that everyone uses the method of screening "antibody pairs" to avoid virus escape, but they are particular about screening "antibody pairs". The two antibodies must cooperate with each other and be able to play a combination boxing, for example, to identify different positions of the virus. Based on the detailed study of the interaction process between virus and antibody, the team finally screened out the "antibody pair" that can inhibit the virus in time and space from 206 candidate antibodies and found the "best partner".

　　Luo Yongqing said that when the antibody was originally designed, the possible virus mutation in the future was considered, so it was not a single antibody, but a pair of antibodies; At the same time, considering the efficacy of the combination therapy, the dosage of "Anbavir monoclonal antibody (1000 mg)+Romisvir monoclonal antibody (1000 mg)" was finally determined, which is also the highest dose of neutralizing antibodies approved at home and abroad.

　　"Even if there are further virus mutations in the future, we can consider other methods, such as continuing to increase the dose to achieve the antiviral effect." Luo Yongqing said.

　　The 2022 SUV is on sale, and the company’s overseas customized batch of cars has arrived in Hong Kong, and a single car can also enjoy wholesale price direct sales. It is the first choice for luxury off-road vehicles. It is a new Cayenne off-road SUV, with multiple models and direct hitting the reserve price. The first batch of reservations has exceeded expectations, and the procedures for the car are complete. Friends who are interested in this model can contact our professional sales manager. For more details, please call and consult the sales manager (see the bottom of the text).

　　Model: 2022 Porsche Cayenne 3.0T Moonlight Blue/m

　　Configuration: 21RS wheel, enhanced luxury bag, SC sports component compass, black sports four-tail-throat exhaust pipe, ring shadow 360, windshield heating, front and rear Porsche logo headrest, wireless charging, floor lamp, black luggage rack, black window slats, panoramic sunroof, front seat heating and ventilation, rear seat heating, smart card, Bose audio lane change assistance, electronic steering, PLUS matrix LED headlights with Porsche dynamic lighting system,

　　The most attractive thing about Porsche Cayenne is its strong sense of science and technology, and the feeling of touching the keys is also very good, so there will be no inconvenience in blind exercise. The car’s roof material is suede, which is very anti-dirty, but it also smells great. The size of the central control panel is 12 inches, which has a good display effect and good maneuverability. And some functions are optional, such as reversing image, which is equipped with 360 degrees and has a good effect. The interior has always been the focus of the Porsche Cayenne, and it is full of technology.

　　One of the highlights of the 22 Porsche Cayennes is the addition of off-road steering assist function, which can reduce the turning radius, improve steering performance and enhance off-road performance with the automatic climbing control system. Prosperity and grandeur reflect each other, deduce the pattern with connotation, and show deep respect for internal cultivation in the details of perfection.

　　The interior design of the 2022 Porsche Cayenne not only inherits the classics, but also innovates in technology. The top leather creates a luxurious cockpit. The multifunctional steering wheel with paddles is not only easy to operate but also comfortable to hold. The traditional five-meter of Porsche also incorporates new technology, a mechanical instrument and four LCD instruments, and its functions are more abundant. The whole design is designed around the driver.

　　The 2022 Porsche Cayenne has a 3.0T V6 engine, a 2.9T V6 twin-turbo engine and a 4.0T V8 twin-turbo engine. The power system is very rich, and the gearbox is equipped with an eight-speed manual transmission. This gearbox has good track performance. After all, Porsche is an instant hit with a sports brand, so now talking about Porsche, besides its luxurious price and the owner’s absolute prestige, the most talked about is its track performance.

　　Company Profile: Tianjin Hongye Tengfei Luxury Car Club is located in Tianjin Port Free Trade Zone, and the company’s physical exhibition hall covers an area of 3,000 square meters. It is a first-class import car wholesale and retail company with comprehensive strength, and its business covers every province and city in China for fifteen years. Adhering to the sales concept of honesty first, it is professional, dedicated and dedicated to serve every customer. We look forward to cooperating with you, and your satisfaction is our greatest pursuit.

　　Main brands: Bentley, Mercedes-Benz, Land Rover, BMW, Porsche, imported Toyota, Lexus, Dodge and other high-end brand models.

　　Main business: foreign car booking, new car sales, car consultation, customized modification and upgrade, national mortgage installment, and acting as an agent for national licensing.

　　Solemnly promise: you can hand over all vehicle procedures: invoice, customs clearance (vehicle import certificate), commodity inspection (quality inspection certificate), vehicle conformity (vehicle configuration certificate), environmental protection list, etc. on the day of car purchase, so as to ensure that customers from all over the country can apply for registration and settle down normally when they return to the local area, and avoid your worries.

　　Company name: Tianjin Hongye Tengfei International Trading Co., Ltd.

　　Sales Manager: 13389982878 Liu Jingli (WeChat synchronization)

　　Company address: Tianjin Binhai New Area Bonded Zone (Hongye Tengfei International Famous Car Plaza)

　　Remarks: Before buying a car, please call the sales manager for details, real-time price, etc. Our company has arranged VIP customers to pick up and drop off buses at the airport and high-speed railway station. Please make an appointment in advance for convenient arrangement. Thank you for your understanding.

　　Disclaimer: The above car purchase preferential information is provided by the comprehensive dealers of this website, and the price fluctuates greatly due to market factors, which is only for car purchase reference; The distributor is responsible for its authenticity, accuracy and legality, and this website does not provide any guarantee or assume any legal responsibility.

● Starting: AMG ONE quasi-production version

　　The 2021 Munich Auto Show officially opened a few days ago. At the auto show, Mercedes -AMG showed the real car of its super sports car AMG ONE quasi-production version. Different from before, the exterior painting of the new car has also been specially designed, which is intended to announce the open world racing game "Extreme Racing: Horizon 5" that this car is about to land.

　　In terms of appearance, the familiar overall shape has been known to everyone since the early prototype of AMG Project ONE. The wide front lip, streamlined body, air inlet and spoiler wing on the roof all indicate that AMG ONE with F1 as the design concept will have a strong aerodynamic effect, which is also the source of the performance of the car.

　　As a prototype close to the production version, we can see that the kit design of the new car has also been improved in details, such as the retractable wing on the front wheel arch, the closed rim cover, the automatic rear spoiler and the exaggerated rear diffuser.

　　The most interesting point of AMG ONE comes from its powertrain. The new car is equipped with the power system from F1 racing cars today. It is composed of a 1.6T V6 internal combustion engine and a kinetic energy recovery system ERS. It was rumored that the comprehensive power of the new car system will exceed 1,200 horsepower. Previously, due to the contradiction between the high idle speed of F1 powertrain and the strict emission regulations of the European Union, the delivery of the new car was delayed many times. However, according to foreign media reports, the delivery of the new car will begin in November this year. I hope that the performance of the production version of AMG ONE will not disappoint the car owners who are waiting hard.

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● Starting: Mercedes-Benz S 680 Guard 4MATIC

　　At the 2021 Munich Auto Show, Mercedes-Benz officially released the S 680 Guard 4MATIC, as a special version of the S-class model, which has the bulletproof standard of the whole vehicle VR10 level and can resist the attack of AK47 and mines.

　　From the appearance, it is not very different from the ordinary new Mercedes-Benz S-Class, and there is no particularly exaggerated design, including the rim, but it is a vehicle with VR10 bulletproof standard. It is equipped with reinforced doors, multi-layer glass and polycarbonate windows with a thickness of more than 1cm, automatic fire extinguishers, emergency air purification system and Michelin PAX bulletproof tires that can last for 30km.

　　The interior part is also a bulletproof upgrade based on luxury, and all the luxury equipment of S-class is basically armed to the top. And its second row of two boss seats can also meet the daily riding and business needs, and even equipped with refrigerators and other equipment.

　　In the case of various bullet-proof enhancements, its curb weight has reached about 5 tons. For such a car like the "tank", it is equipped with a 6.0T twin-turbocharged V12 engine with a maximum power of 612 HP and a peak torque of 830 Nm.

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● Starting: Mercedes-Benz G-Class PROFESSIONAL Line (professional suit)

　　At the 2021 Munich Auto Show, Mercedes-Benz brought a strong lineup of electric vehicles, and at the same time, the Mercedes-Benz G-class PROFESSIONAL Line (professional suit) based on the new generation of G-class also made its debut at the auto show.

　　PROFESSIONAL versions have been introduced in G-class in past dynasties. Compared with the ordinary G-class which gradually moves towards luxury route, the PROFESSIONAL version has returned to the original form of G-class, and has become the characteristics of new cars with strong off-road performance and reliability. However, the PROFESSIONAL version based on the new generation G-class only provides the appearance kit.

　　The classic square box shape seems to have a reliable feeling without any modification. Of course, Mercedes-Benz has equipped this product with a brand-new big lampshade to protect the lamp group. In addition, the brand-new 18-inch five-spoke wheels, matching off-road tires and fenders also make the new car look more interesting.

　　In addition, the brand-new roof rack and climbing ladder seem to be able to support more professional equipment for you. At the same time, the brand-new external spare tire rack adopts a more concise design style, which is easy to pick up and more secure.

　　This official first-time model adopts a brand-new "orange copper" car paint, and this part will also be one of the customization projects, including the appearance and interior of the new car at the same time. In addition to some new kits mentioned above, customers can also make additional customization. In terms of power, it depends on the specific power model selected by the owner. The display vehicle is equipped with a Mercedes-Benz 3.0T diesel six-cylinder engine with a maximum power of 286 HP and a peak torque of 600 Nm.

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● Starting: Audi grandsphere concept car

　　At the 2021 Munich Motor Show, the Audi grandsphere concept car was officially unveiled. The official map of the new car has been released before. As the second model in the "sphere" concept car, the technology and design features of the application of the grandsphere concept car will be extended to the future production models under the Audi brand in a few years.

　　In terms of appearance, the new car adopts a futuristic design language. The polygonal front grille with a wide front face adopts a rather complicated middle net layout. In addition, the new car is equipped with a sharp headlight group, and the interior adopts a rather simple light source layout. In addition, the two sides of the front enclosure of the new car are also equipped with sharp guide grooves, which can further optimize the aerodynamic performance of the vehicle.

　　Coming to the side of the car, the new car has a smooth roof line, which is very slender with the design of short front suspension and long rear suspension. The "sexy" tail line also gives the new car a different charm. In terms of body size, the length, width and height of the new car are 5350/2000/1390mm and the wheelbase is 3190mm respectively. The low body height can fully display the sports attributes of the vehicle. In addition, the new car will adopt a door-to-door design, which can make passengers get on and off more calmly.

　　When it comes to the rear of the car, its shape is no less than that of the front of the car. The sharp taillight group can form a good echo with the headlight group, and the light source layout with a sense of science and technology will be adopted inside the lamp group. In addition, the new car also adopts a design with visual impact at the rear enclosure, and the design similar to the diffuser can further optimize the aerodynamic performance of the vehicle.

　　The interior of the new car will be built into a more comfortable living/experience space. Before the driving mode is turned on, the steering wheel, dashboard and other devices will be hidden, which will not only make the car have more open space, but also further demonstrate the sense of technology of the vehicle. In addition, the quality of the new car in the details will also be the ultimate. The blessing of a large number of materials such as wood, wool, synthetic textile fabrics and metals can make the car have a warmer atmosphere, just like being in your own living room.

　　In terms of power, the new car will be built on the PPE platform. It is reported that the new car will be equipped with a motor on the front and rear axles, with a maximum power of 530 kW and a peak torque of 960 Nm. At the same time, the quattro four-wheel drive system will not be absent. In terms of cruising range, the cruising range of the new car will exceed 750 kilometers.

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● Starting: Renault 5 electric concept car

　　At the 2021 Munich Motor Show, the Renault 5 electric concept car officially debuted. Renault 5 used to be a three-door hatchback mini-car and sold well in the European market from 1970 to 1985, but it will be revived as a pure electric car.

The picture shows Renault 5 Turbo』.

　　Compared with the slimness and gentleness of the original Renault 5, the Renault 5 electric concept car has become more full. Because of the positioning of electric vehicles, the proportion of the engine compartment of the new car to the total length of the car body is not as high as that of the old one, and the short engine compartment also means better interior space. At the same time, the concept car uses a larger rim, which is matched with the obvious shoulder lines on the front and rear fenders, and the overall visual effect is more powerful, which is also an obvious feature of the Renault 5 Turbo model.

　　In the details of the body shape, the designer’s tribute to the classic Renault 5 is also full of delicate thoughts. For example, the front composed of a large number of straight lines and rectangles is easy to think of the simple front bumper and headlights of the first generation Renault 5 written by Michel Boue. The imitation air intake design at both ends of the front bumper of the new car is also decorated with square LED light bars, which echoes the rectangular light group on the classic model.

The picture shows Renault 5 Turbo』.

　　The design of the new car’s tail can’t help but make people exclaim exquisitely. While inheriting the C-pillar angle and the straight tailgate of the original Renault 5, the overall shape of the taillight group also draws inspiration from the old model, and combines the creativity at that time in height and LED light source structure. Moreover, the taillight of the new car is also connected by two LED strip that run through the tailgate, and the right side of the light belt is decorated with Renault diamond trademark shape and the number "5". In fact, there are many elements about "5" in the Renault 5 concept car, such as the part near the daytime running lights and the front door edge near the fender.

　　Renault did not disclose more information about the interior and power of the new car. In addition, at the press conference, Renault also said that it plans to release seven brand-new pure electric products before 2025. As a small electric vehicle, the new Renault 5 will replace Zoe, who has already achieved success, as the new main sales player, and there will be a smaller Renault 4 to join the brand’s pure electric plan.

● Starting: Cupra UrbanRebel concept car

　　The 2021 Munich Auto Show officially opened a few days ago, and Cupra, a high-performance brand of SEAT, officially released the UrbanRebel concept car. The new car is driven by pure electricity, and its design is exaggerated and fighting.

　　In the front part, the new car is built in a rather exaggerated design language. A sharp headlight group will appear on the new car, with a relatively simple light source layout inside and strong sci-fi attributes. In addition, the new car will be equipped with a large trapezoidal vent in the front enclosure, and the radical front lip and sharp guide grooves on both sides can create a more intense fighting atmosphere.

　　Coming to the car side, the new car adopts a two-door body layout, and at the same time, the black roof design will also appear on the new car. In addition, we can see that the new car will adopt a three-dimensional design at the side skirt, which is expected to further optimize the aerodynamic performance of the vehicle.

　　In the rear part, the new car adopts a highly recognizable design, and the exaggerated spoiler is quite eye-catching. It is worth mentioning that the taillight group of the new car will be integrated on the spoiler, which is very rare in the current automobile market. In addition, the other parts of the rear of the car are basically occupied by aerodynamic kits, and the exaggerated diffuser and the diversion grooves on both sides can play a positive role in the performance of the vehicle.

　　In terms of power, the maximum power of the driving motor equipped with the new car will reach 320 kW (435 HP), and it only takes 3.2 seconds for the new car to accelerate from standstill to 100 km/h.

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● Starting: Kia SPORTAGE GT-line European Edition

　　At the 2021 Munich Motor Show, Kia launched the SPORTAGE GT-line European version. The new car has a more sporty design and a shorter wheelbase than other regional versions. The previous model of this car is called Lion Run in China, and this generation of SPORTAGE is also expected to take the lead in meeting you as a brand new KX5 in China.

　　In terms of appearance, at the beginning of this year, Kia released a brand-new design concept of "Opposites United", which naturally became the inspiration for the design of the new SPORTAGE. The black air intake grille at the front of the car has a complicated shape, and the exaggerated LED daytime running lights on both sides are connected with the headlight group, which looks very individual.

　　The concave-convex shape of the taillights is different from the flat and penetrating design that is popular now. The internal LED strip echoes the daytime running lights at the front of the car, adding a sense of movement to the rear of the car. The new car is built on the N3 platform. In terms of size, the length of the European version is 4515mm, which is 85mm shorter than the global version, and the wheelbase is 2680mm, which is 75mm shorter than the global version.

　　In the interior, the new Kia SPORTAGE GT-line adopts a penetrating instrument panel, the LCD instrument panel is integrated with the central control panel, the three-spoke steering wheel is added with GT exclusive LOGO, and the transmission is knob-type. The paint decoration makes the knob shifting mechanism more like a work of art, and the GT exclusive LOGO is also added to the vehicle seat.

　　In terms of power, the new car offers a variety of power combinations, including 1.6T (gasoline +48V light mixing system, with maximum power of 150 horsepower version and 180 horsepower version. In addition, the new car will also be equipped with a 1.6T plug-in hybrid powertrain, with a combined maximum power of 264 HP and a 13.8kWh battery pack, with a mileage of 56km in pure electric form.